Vitamin B12 tsis muaj peev xwm yog ib qho ntawm feem ntau muaj kev noj haus tsis zoo. Nws ua rau muaj cov tsos mob, xws li qaug zog, tsis nco qab thiab tingling ntawm txhais tes thiab taw. Yog vim li cas rau ntau cov kev mob tshwm sim yog tias vitamin B12 plays lub luag hauj lwm loj hauv ntau lub cev.
Vitamin B12 Ua Li Cas?
Vitamin B12 muaj ib qho tseem ceeb hauv kev tsim cov DNA, uas yog lub cev txoj caj ces.
DNA coj ncaj ntawm txhua qhov ntawm lub cev.
Vitamin B12 kuj thiaj li tau homocysteine, ib qho ntawm lub cev qhov tshwm sim tshuaj. Yog tias homocysteine tsis zoo rau metabolized, ces nws ua rau muaj mob thiab muaj kev puas tsuaj rau lub cev.
Cov tsos mob thiab cov teebmeem ntawm Vitamin B12 Deficiency
Anemia yog ploj zuj zus ntawm cov qe ntshav liab (RBCs). Tus thawj ntawm qhov kev ntsuam xyuas ntawm B12 deficiency yog megaloblastic anemia, uas yog hom tshuaj anemia uas feem ntau ua rau qaug zog thiab tachycardia (lub plawv dhia ceev ceev), thiab qee zaum kiv taub hau. Vitamin B12 yog ib yam khoom noj uas yuav tsum tau muaj rau cov ntshav liab. RBCs muab lub zog ua cov pa oxygen thoob plaws lub cev kom muaj hwj chim tag nrho cov kev xav tau ntawm lub cev.
Megaloblastic anemia tuaj yeem kuaj tau los ntawm kev kuaj ntshav.
Peripheral neuropathy yog ib hom mob paj hlwb. Qhov no txhais tau hais tias qab haus huv lawv tus kheej yuav raug puas ntsoog los yog muaj ib qho tsis muaj peev xwm ntawm myelin.
Myelin yog ib qho kev tiv thaiv ntawm cov hlab ntsha ntawm peripheral. Vitamin B12 yog ib qho kev sib tw hauv myelin tsim, thiab yog li cov vitamin B12 deficiency tiv thaiv myelin ntawm kev ua raws li xav tau.
Nrog B12 deficiency, cov paj hlwb ncaj qha nrog rau txo ntawm myelin cuam tshuam nrog cov hlab ntsha ua haujlwm. Lub peripheral qab haus huv tswj kev txav thiab kev xav ntawm lub cev.
Cov tsos mob ntawm peripheral neuropathy feem ntau tshwm rau taw thiab ob txhais tes, thiab muaj peev xwm yuav ncav cuag cov caj npab thiab txhais taw thiab. Cov tsos mob tshwm sim muaj xws li:
- Tingling
- Tsis siab
- Tsis muaj zog
Dementia yog ib qho kab mob ua cim los ntawm kev nco thiab kev coj tus cwj pwm. Muaj ntau yam ua rau dementia, thiab vitamin B12 tsis muaj peev xwm yog ib qho ntawm cov neeg tsis paub ntau vim nyuam qhuav ua rau. Cov kev tshawb fawb pom zoo hais tias qhov kev vam ncua nrog vitamin B12 tsis muaj peev xwm ua rau ntawm qib siab homocysteine.
Cov tsos mob ntawm dementia muaj xws li:
- Tsis nco qab
- Tsis tuaj yeem
- Teeb meem daws teeb meem
- Tsis muaj peev xwm mloog zoo
- Tsis muaj peev xwm tu nws tus kheej
- Txaus siab rau
- Kev hnov kev pom
Kev nyuaj siab yog ib qho ua tau ntawm cov vitamin B12 tsis muaj peev xwm, thiab tej zaum yuav muaj ntshav qab zib los yog mob ntshav tsis nto.
Mob stroke yog ib yam mob uas cuam tshuam ntawm kev cuam tshuam ntawm cov ntshav khiav mus rau lub hlwb, ua rau muaj kev xiam oob khab lossis lub hlwb. Cov Vitamin B12 tsis muaj peev xwm yuav ua rau muaj kev pheej hmoo ntawm qog nqaij hlav ntawm cov neeg hluas uas tsis yog muaj feem yuav mob stroke. Txawm yog los tsis muaj qhov txuas yog qhov muaj teeb meem heev, thiab qhov kev pheej hmoo yuav tshwm sim los ntawm ntau ntau homocysteine.
Myelopathy txhais tau tias tus kab mob ntawm tus txha caj qaum. Vitamin B12 deficiency ua rau ib hom kab mob qaum hu ua subacute ua ke degeneration ntawm tus txha nqaj qaum, uas yog poob ntawm cov tshuaj tiv thaiv mei ntawm qee qhov chaw ntawm tus txha caj qaum uas tswj lub sijhawm, tshuav nyiaj li cas thiab kev xav.
Cov tsos mob ntawm kev sib txuam sib txuam ua ke ntawm tus txha caj qaum muaj xws li:
- Tsis muaj zog
- Kev loog, tingling
- Spasticity
- Qhov teeb meem seem nyiaj
Cov kua nplaum nplaum kuj yog los ntawm vitamin B12 deficiency. Glossitis yog lub npe siv los piav txog kev mob siab, tsis paub hais lus npliag lus uas tuaj yeem tshwm sim los ntawm qhov kev noj haus tsis txaus.
Tej Kev Mob Uas Muaj Feem xyuam nrog Vitamin B12 Deficiency
Tus kab mob thyroid thiab Multiple Sclerosis (MS) yog ob qho kev ntseeg tias muaj feem xyuam rau txoj kev kho mob autoimmune. Tus kab mob autoimmune yog ib yam mob los ntawm lub cev tua nws tus kheej.
Cov tshuaj tiv thaiv kev mob hlwb yog ib hom kab mob uas tshwm sim los ntawm tus kab mob autoimmune uas tshwm sim los ntawm kev tua tus kheej rau thaj tsam ntawm lub plab uas muaj feem xyuam rau cov vitamin B12 absorption.
Feem ntau, cov neeg uas muaj tus kab mob thyroid los yog MS kuj muaj qhov tsis zoo rau qhov tsis zoo thiab nws cov vitamin B12 tsis muaj peev xwm.
Ua rau Vitamin B12 Deficiency
Tsawg Dietary Intake
Qhov feem ntau ua rau cov vitamin B12 tsis muaj peev xwm yog tsis muaj vitamin B12 ntawm kev noj haus. Vitamin B12 yog ib yam khoom noj uas tsuas pom muaj nyob rau hauv cov khoom tsiaj xws li nqaij, nqaij qaib, ntses, qe thiab nqaij. Yog li cov vegans no tseem ceeb tshaj plaws ntawm kev noj haus tsis tshua zoo txog cov vitamin B12, xws li cov neeg tsis vegan uas tsis noj txaus cov vitamin B12 nplua nuj khoom noj.
Qee yam zaub mov muaj zog nrog vitamin B12, thiab yog tias koj xav tau koj cov vitamin B12 los ntawm cov khoom noj khoom haus vegan, koj yuav tsum mob siab nrhiav cov zaub mov no.
Tsawg Zog
Vitamin B12 yog absorbed los ntawm cov hnyuv me, tab sis nws yuav tsum tau ua qee yam kev ua ntej hauv plab ua ntej. Yog li, qee qhov kev mob uas cuam tshuam rau lub plab los yog txoj hnyuv me me tuaj yeem cuam tshuam nrog cov vitamin B12 kom haum. Qhov tseem ceeb tshaj plaws yog ib qho protein uas ua rau lub plab ua ke nrog cov vitamin B12 ua ntej nws yuav nqus tau rau hauv cov hnyuv.
Tus kab mob autoimmune, gastric bypass phais thiab kev mob ntawm lub plab yog txhua yam teeb meem uas cuam tshuam nrog cov khoom noj thiab kev ua haujlwm ntawm qhov tseem ceeb, thiab yog li cov vitamin B12 nyob rau hauv kev noj haus yuav tsis haum txaus rau hauv lub cev, thiab qhov no, nws yog tshem tawm ntawm cov quav taw.
Kev siv cawv ntau heev ua rau hloov hauv plab ntawm lub plab, cuam tshuam nrog ntau tshaj qhov tseem ceeb, ua rau B12 tsis muaj peev xwm.
Tus kab mob hnoos hnoos xws li Crohn tus kab mob thiab Celiac Cov kab mob tuaj yeem tiv thaiv kom tsis haum ntawm vitamin B12 hauv cov hnyuv me, ua qhov tsis muaj peev xwm txawm tias muaj vitamin B12 txaus noj.
Pernicious anemia yog ib hom kab mob autoimmune uas txo los yog tshem tawm qhov tseem ceeb, qhov protein nyob rau hauv lub plab uas khi cov kabmob B12 thiaj li hais tias nws muaj peev xwm muab absorbed. Qhov no ua rau B12 deficiency los ntawm malabsorption. Hom tshuaj B12 no tsis tuaj yeem raug kho nrog B12 hloov qhov ncauj, thiab yuav tsum muaj kev kho mob nrog vitamin B12 txhaj tshuaj.
Cov tsos mob ntawm pernicious anemia muaj xws li:
- Nkees
- Tsis muaj zog
- Lightheadedness
- Kev nyuaj siab
- Mob taub hau
- Lub plawv dhia ceev ceev
- Hu rau hauv pob ntseg
Cov tshuaj yuav cuam tshuam nrog vitamin B12 nqus dej. Feem ntau cov tshuaj uas ua rau cov vitamin B12 tsawg theem muaj xws li:
Metformin: ib qho tshuaj siv los kho ntshav qab zib
Colchicine: ib qho tshuaj siv los kho gout
Chloramphenicol: ib qho tshuaj tua kab mob siv los kho cov kab mob
Ntau cov tshuaj siv rau kev kho mob siab
Lo Lus Ntawm
Yog tias koj muaj vitamin B12 tsis muaj peev xwm, ntau cov teebmeem tau hloov, tshwj xeeb tshaj yog thaum ntxov. Feem ntau, yog tias koj cov vitamins B12 tsis tuaj yeem yog los ntawm kev noj zaub mov tsis zoo, cov tshuaj noj los yog cov zaub mov muaj zog tuaj yeem pab txhim kho koj cov vitamin B12.
Yog tias lub cev tsis haum xeeb yog vim li cas koj cov vitamins B12 tsis ua haujlwm, nws feem ntau xav tias koj yuav siv tau koj cov tshuaj vitamin B12 los ntawm qhov ncauj los ntawm qhov ncauj, vim qhov no pub rau tus cev kom nkag mus rau hauv cov ntaub so ntswg.
> Qhov chaw:
> Cerit L, Duygu H, Gulsen K, Kemal H, Tosun O, Ozcem B, Cer Z, Gunels A, Kardiol Pol. Qhov sib piv ntawm vitamin B12 thiab SYNTAX tau. 2017; 75 (1): 65-70.
> Luciana Hannibal, Vegard Lysne, Anne-Lise Bjørke-Monsen, Sidney Behringer, Sarah C. Grünert, Ute Spiekerkoetter, Donald W. Jacobsen, thiab Henk J. Blom, Biomarkers thiab Algorithms rau Kev Ntseeg Vitamin B 12 Deficiency, Lub Nruab Zaum Biosci. 2016; 3: 27, ua: 10.3389 / fmolb.2016.00027